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Award WinnerBio-Tech FormulaLongevity Technology

Supreme Night Secret

A chronobiological night cream designed to support the skin’s natural overnight repair and regeneration processes.

"The night is when skin performs its most important repair work. Supreme Night Secret is formulated to work with that process, not against it. Chronodyn boosts cellular energy during the skin's peak repair window, while Juvinity targets ageing at the cell nucleus to support skin longevity from within." –Dr Sebagh

Sale price£195.00

Suitable For

  • Gray circle with a white plus sign in the centerAll Skin Types
  • Gray circle with a white plus sign in the centerMature Skin
  • Gray circle with a white plus sign in the centerDry Skin
  • Gray circle with a white plus sign in the centerSkin with Early to Advanced Signs of Ageing.
  • Gray circle with a white plus sign in the centerDehydrated Skin

Targets

  • Gray circle with a white plus sign in the centerFine Lines & Wrinkles
  • Gray circle with a white plus sign in the centerAnti-Ageing
  • Gray circle with a white plus sign in the centerLoss of Firmness
  • Gray circle with a white plus sign in the centerCellular Ageing
  • Gray circle with a white plus sign in the centerOxidative Stress
  • Gray circle with a white plus sign in the centerBarrier Weakness

Winner, Harper's Bazaar Best Night Cream for Mature Skin.

An advanced anti-ageing night cream formulated to work in harmony with the skin's natural overnight regenerative cycle. Supreme Night Secret combines chronobiology active Chronodyn and longevity active Juvinity with a nourishing complex of bio-tech extracts and barrier-repair oils to boost cellular energy, protect against cellular ageing and restore firmness and radiance while you sleep.

The science of overnight skin repair.

Chronodyn synchronises with the skin's circadian rhythm during the night phase, when cellular repair is at its peak. By increasing cellular energy (ATP) production, it amplifies the skin's natural recovery process, leaving skin visibly firmer and less fatigued by morning.

Longevity technology at the cell nucleus.

Juvinity targets ageing at the cell nucleus, encouraging skin cells to behave like younger, healthier cells. It limits telomere shortening and oxidative stress to support optimum cell metabolism, so skin not only recovers overnight but ages more slowly over time.

Nourishment and regeneration through the night.

Euglena Gracilis Extract, a nutrient-dense microalgae rich in the unique beta-glucan paramylon, supports the skin's natural defence and repair mechanisms overnight. Date Palm Kernel Extract, rich in isoflavones and phytosterols, stimulates collagen production and improves elasticity. A replenishing blend of plant oils, Hyaluronic Acid and Rapeseed Phytosterols nourishes the skin barrier, delivering intense hydration and protection against oxidative stress. By morning, skin appears smoother, firmer, plumper and more radiant.

"This cream really is the next best thing to booking an appointment at Dr Sebagh's London clinic." - Net A Porter

Key Ingredients and Actives

Euglena Gracilis Extract (Chronodyn)

a pseudo algae that works with the skin’s overnight restorative cycle, known as the ‘cutaneous biological clock’, to increase the release of calcium and production of ATP (adenosine triphosphate) molecules, helping tone and re-firm the skin and erase the signs of fatigue.

Juvinity

This pioneering active ingredient combats the ageing of the cell’s nucleus, encouraging it to behave like a young cell and so delaying the metabolic and nucleus senescence (the process of deterioration with age). It also limits oxidative stress and Telomeres shortening to ensure optimum metabolism and the replication of young cells.

Phoenix Dactylifera (Date) Seed Extract

a plant-derived active ingredient extracted from the date-palm kernel. A source of isoflavones, ursolic acid, phytosterols, antioxidant tocotrienols and Vitamin A. Improves skin elasticity, stimulates fibroblasts and collagen production, increased skin hydration and an anti-inflammatory effect. Proven to have a significant impact on the visible signs of skin ageing, including the appearance of fine lines and wrinkles.

Shea Butter

powerful emollient moisturiser to soothe the skin. Rich in antioxidants including vitamins A, E, F as well as flavonoids and EGCG to prevent the formation of wrinkles, improving moisture retention and smoothing skin texture.

Rosa Canina Fruit (Rosehip Seed) Oil

renowned for its naturally anti-ageing, antioxidant and replenishing benefits. This oil is particularly rich in the essential fatty acids which play an important role in the process of regenerating the skin’s natural barrier. It also assists in the hydration of the skin by preventing water loss, ensuring a supple texture and helping to protect skin against premature ageing.

Sesame Seed Oil

rich in nourishing and moisturising fatty acids (especially oleic and linoleic acid) to maintain the skin barrier. The presence of antioxidant Vitamin E neutralises free radicals and protects against oxidative stress.

Wheat Germ Oil

one of the highest concentrations of antioxidant Vitamin E in any plant oil. Rich in moisturising fatty acids to moisturise and repair the skin's essential barrier.

Rapeseed Sterols

plant sterols (phytosterols) have been shown to inhibit enzymes which degenerate collagen fibres, slowing the loss of elasticity that comes with age. Promotes cellular regeneration, boosting collagen and hyaluronic acid synthesis to repair the skin barrier, reducing TEWL. Also known to have skin-soothing, anti-inflammatory benefits.

Hyaluronic Acid & Rhizobian Gum

activates moisturisation, maintains the integrity of skin structure and leaves skin with a satin-like texture. Hyaluronic acid, naturally present in the skin, acts like a biological sponge, both attracting and retaining moisture within the epidermis.

Biosaccharide Gum-4

provides anti-pollution benefits, helping to protect skin against external aggressors. This polysaccharide, extracted from corn, forms a three-dimensional matrix which acts like a suit of armour and helps to shield the skin against atmospheric pollution.

AQUA (WATER), CYCLOPENTASILOXANE, GLYCERYL STEARATE, GLYCERIN, DICAPRYLYL ETHER, PEG-12, CAPRYLIC/CAPRIC TRIGLYCERIDE, EUGLENA GRACILIS EXTRACT, CETEARETH-20, BIOSACCHARIDE GUM-4, CETEARYL ALCOHOL, POLYACRYLATE-13, BUTYROSPERMUM PARKII (SHEA) BUTTER, DIMETHICONE, POLYMETHYL METHACRYLATE, HYDROGENATED PALM KERNEL GLYCERIDES, CETEARETH-12, CAPRYLIC/CAPRIC/SUCCINIC TRIGLYCERIDE, PHENOXYETHANOL, GLYCERYL DIBEHENATE, POLYISOBUTENE, ROSA CANINA FRUIT OIL, AROMA (FLAVOR), CETYL ALCOHOL, TRIBEHENIN, ALPHA-GLUCAN OLIGOSACCHARIDE, PROPANEDIOL, CHLORPHENESIN, CAPRYLYL GLYCOL, SESAMUM INDICUM (SESAME) SEED OIL, GLYCERYL BEHENATE, PEG-75 STEARATE, SAFFLOWER OIL / PALM OIL AMINOPROPANEDIOL ESTERS, POLYSORBATE 20, HYDROGENATED PALM GLYCERIDE, BHT, CETETH-20, STEARETH-20, TRITICUM VULGARE (WHEAT) GERM OIL, ALGIN, GERANYLGERANYLISOPROPANOL, PHOENIX DACTYLIFERA (DATE) SEED EXTRACT, TOCOPHERYL ACETATE, BRASSICA CAMPESTRIS (RAPESEED) STEROLS, RHIZOBIAN GUM, SODIUM HYALURONATE, POTASSIUM SORBATE, TOCOPHEROL, CI 14700 (RED4), CITRONELLOL, BENZYL ALCOHOL, GERANIOL

Application

Apply Dr Sebagh Supreme Night Secret for the face and neck before bed to thoroughly cleansed skin. For maximum benefit, layer Supreme Night Secret over Dr Sebagh Supreme Maintenance Youth Serum or mix a couple of drops of the serum with the cream before application.

Benefits
  • Supports the skin’s overnight regenerative cycle to help repair and renew while you sleep
  • Boosts cellular energy (ATP) to reduce visible signs of fatigue and restore skin vitality
  • Delays cellular ageing by supporting the longevity of the skin cell nucleus
  • Stimulates collagen production to improve firmness and skin elasticity
  • Deeply nourishes and restores the skin barrier to reduce moisture loss
  • Provides intense overnight hydration to leave skin smoother, plumper and more supple by morning
  • Protects against oxidative stress and environmental ageing with powerful antioxidants
FAQs

What is the best night cream for mature skin? 

The best night cream for mature skin works with the skin's biological clock rather than simply sitting on the surface overnight. Supreme Night Secret is formulated with Chronodyn and Juvinity, two pioneering biotech actives that sync with the skin's natural overnight repair cycle to combat nucleus ageing, boost cellular energy and support skin longevity. Voted Best Night Cream for Mature Skin by Harper's Bazaar, it delivers visibly firmer, smoother and more radiant skin by morning.

Why should you use a night cream? 

Night is when the skin does its most intensive repair work. Cell renewal accelerates, collagen production increases and the skin barrier restores itself. A targeted night cream amplifies this natural process, delivering actives at the moment when the skin is most receptive to them. Supreme Night Secret is specifically designed to work in sync with this biological rhythm for maximum overnight results.

What does Supreme Night Secret do? 

Supreme Night Secret works on multiple levels while you sleep. Chronodyn boosts ATP cellular energy and calcium release to re-firm and tone the skin. Juvinity combats nucleus ageing and prevents Telomere shortening, encouraging skin cells to behave younger over time. Together they deliver visibly firmer, smoother and more radiant skin by morning, with long-term improvement in skin structure and elasticity.

At what age should you start using Supreme Night Secret? 

Supreme Night Secret is most beneficial from your forties onwards, when the visible signs of cellular ageing, loss of firmness and reduced collagen production become more pronounced. However if you are in your late thirties and beginning to notice loss of elasticity or deeper lines, it is an excellent time to start. Earlier use means longer-term results.

Can Supreme Night Secret help with wrinkles and loss of firmness?

Yes. The formula targets both surface wrinkles and the deeper structural causes of skin ageing. Biotech peptides stimulate collagen synthesis and improve elasticity, while the tense-and-lift complex firms and tones overnight. With continued use, skin appears measurably smoother, firmer and more lifted.

Is Supreme Night Secret suitable for sensitive or dry skin? 

Yes. Despite its advanced biotech formula, Supreme Night Secret is suitable for all skin types including sensitive and dry. Hyaluronic acid, antioxidant plant oils and nourishing lipids restore hydration, strengthen the skin barrier and prevent moisture loss overnight, so skin wakes up comfortable and nourished as well as visibly younger-looking.

How do I get the most out of Supreme Night Secret? 

Apply every evening to cleansed skin as the final step in your routine. For an intensive overnight treatment, mix with a few drops of Serum Repair for added plumping and hydration, or blend with Pure Vitamin C Powder Cream to brighten dull or uneven skin tone. A little goes a long way — use the spatula provided and smooth gently over the face and neck.

What is the difference between Supreme Day Cream and Supreme Night Secret? 

Supreme Day Cream is your daily environmental shield, protecting against HEV blue light, pollution and free radicals while firming and illuminating throughout the day. Supreme Night Secret is your overnight cellular regeneration treatment, working with the skin's biological repair cycle to combat ageing at a deeper structural level while you sleep. Used together as a morning and evening ritual, they form the most complete anti-ageing routine in the Dr Sebagh range.

Dr Sebagh Supreme Night Secret face and neck cream with red packaging box
Supreme Night SecretWith box Sale price£195.00

Compare With...

Dr Sebagh Supreme Night Secret face and neck cream jar for overnight skin regenerationSupreme Night Secret
  • Cellular Longevity Overnight Cream

    Chronodyn and Juvinity work with the skin's biological clock to combat nucleus ageing while you sleep.

  • Prevents Telomere Shortening

    Pioneering biotech actives encourage cells to behave younger, slowing the visible ageing process at source.

  • Firms, Tones & Erases Fatigue

    Stimulates ATP cellular energy and calcium release to re-firm skin and restore a rested, radiant look.

  • Restructures & Repairs the Skin Barrier

    Reduces inflammation and deeply repairs dry or damaged skin overnight for visibly renewed skin by morning.

  • Targeted Moisture for Mature & Menopausal Skin

    Specifically formulated to address dryness, loss of elasticity and dehydration caused by hormonal changes.

  • Restructures & Replenishes the Skin Barrier

    Essential lipids and seaweed extracts restore the hydrolipic film and prevent moisture loss.

  • Boosts Collagen Synthesis

    Retinyl Palmitate and Vitamin E promote cell turnover, improve skin tone and increase dermal thickness.

  • Soothes Redness & Sensitivity

    Magnesium, zinc and anti-inflammatory amino acids calm reactive, sensitive or compromised skin.

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